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Pragmatic trials are studies designed to provide information for the practice of clinical trials in real life. They are usually focused on the practical aspects of the research design, like the recruitment process and consent, adherence, and the use of commonly available equipment.
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A pragmatic trial that uses a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is necessary for practical trials to be valid and also reduces bias in the results. However, too much heterogeneity can lead to issues with the design of the trial.
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The purpose of pragmatic trials is to mimic real-life scenarios and gain maximum validity externally. They are usually ordered by policymakers and practitioners to help guide their decisions. They can also be a great method to determine the causal relationship between an intervention and 프라그마틱 정품확인 정품 (socialevity.com) its outcomes. They should, however, not, be used to replace explanatory studies.
The pragmatism idea is controversial and there are concerns about whether pragmatic trials can replace explanatory tests or if they should serve as an addition to them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, that inform policy and practice decision-making. They also proposed the framework for pragmatic trials, dubbed PRECIS.2 This tool was designed to define the features of a pragmatic trial that include the recruitment process, the design and delivery of the intervention, 프라그마틱 정품 and the follow-up.
The number of pragmatic trials is increasing. A recent Medline query using the keywords naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), returned 34 articles. These are shown in red on Figure 2. This is an indication that the health sciences community is becoming increasingly sensitized to the issue of pragmatics. It is important to remember, however, 프라그마틱 슬롯체험 that the majority of these studies were conducted in primary care settings.
